NEWPORT BEACH, Calif. – December 8, 2005 – The TriZetto Group Inc. (NASDAQ: TZIX) announced that Blue Cross and Blue Shield of Kansas City has become the seventh major health plan to select TriZetto's CareAdvance™ Enterprise software to automate its case, disease and population management programs. The CareAdvance solution, which TriZetto introduced in May 2004, is gaining rapid market adoption and is expected to be managing care for more than six million health plan members nationwide by the end of 2006. An additional three million members may be added upon the completion of the pending acquisition of CareKey Inc., which TriZetto announced last month.

CareAdvance Enterprise will be tightly integrated with Blue Cross and Blue Shield of Kansas City's Facets® administrative software, in use since 1999. Last year, the company upgraded to Facets Extended Enterprise™ (Facets e2), the latest version of the software, and has also purchased multiple specialized software components from TriZetto, including the HealthWeb® Internet platform for conducting business online with constituents; the NetworX Pricer™ and NetworX Modeler™ applications for advanced contract management; and the Facets e2 Defined Contribution module to administer consumer-directed healthcare benefit plans.

According to Dr. Blake Williamson, vice president and medical director for Blue Cross and Blue Shield of Kansas City, CareAdvance Enterprise will enable the health plan to expand its successful chronic disease management programs and to eventually offer innovative, preventive wellness programs to all of its 880,000 members.

"CareAdvance Enterprise will help us to quickly identify members with specific medical conditions for proactive treatment programs," said Williamson. "The technology will also support real-time, electronic communication among members, providers and health plan staff. That sophisticated functionality will allow us to implement programs that can help all our members better manage their care, make smart lifestyle choices and, ultimately, lead healthier lives."

"Medical management is a key area in which technology can be a health plan's best ally for reducing costs," said Robert London, M.D., TriZetto's chief clinical officer. "CareAdvance Enterprise is a highly functional system that can help our customers improve price and quality of care, while engaging their members with value-added services that tighten the relationship between the health plan and the consumer."

CareAdvance Enterprise is a single platform for automating case, disease and population management. Tightly integrated with claims and other core systems, this patient-centric solution provides complete coverage, "from claim to consumer." CareAdvance Enterprise automates all aspects of care management, including: member identification and assessment; guideline-based care planning; member and provider communications; task and team management; ongoing member monitoring, education and care coaching; and reporting for a variety of constituents.

In November, TriZetto announced that it is acquiring CareKey, the advanced care management software provider that jointly developed the CareAdvance Enterprise product suite with TriZetto. This acquisition is part of TriZetto's overall commitment to provide technology to assist healthcare payers in addressing both administrative and medical costs.

"TriZetto has a strong history serving the core administration needs of Blue Cross and Blue Shield plans," added London. "Over the last two years, we have dramatically expanded the ways we can assist health plans in capitalizing on the rise of consumer-centered healthcare. In addition to our traditional benefit plan administration, TriZetto now also offers integrated solutions for fund, care and provider network management."

About Blue Cross Blue Shield of Kansas City

Blue Cross and Blue Shield of Kansas City, the largest not-for-profit health insurer in the state and the only not-for-profit health insurer in Kansas City, has been part of the Kansas City community since 1938. BCBSKC provides health coverage to more than 880,000 residents in the greater Kansas City area and Northwest Missouri. Blue Cross and Blue Shield of Kansas City is an independent licensee of the Blue Cross and Blue Shield Association. For more information on the company, visit their Web site at www.bcbskc.com.

About TriZetto

TriZetto serves the payer market, comprised of national and regional health insurance plans as well as benefits administrators, which provide transaction services to self-insured employer groups. The company offers a broad portfolio of information technology products - software, outsourcing services, and consulting services - tailored to the needs of healthcare payers. Headquartered in Newport Beach, Calif., TriZetto can be reached at (949) 719-2200 or www.trizetto.com.

Important Notice Regarding Forward-Looking Statements

This press release contains forward-looking statements that involve risks and uncertainties. The forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements may include statements about future revenue, profits, cash flows and financial results, the market for TriZetto's and CareKey's services, future service offerings, industry trends, client and partner relationships, TriZetto's and CareKey's operational capabilities, future financial structure, uses of cash, acquisitions or proposed transactions. Actual results may differ materially from those stated in any forward-looking statements based on a number of factors, including the ability of TriZetto to successfully integrate the businesses of TriZetto and CareKey; the contributions of CareKey to TriZetto's operating results; the effectiveness of TriZetto's implementation of its business plan, the market's acceptance of TriZetto's new and existing products and services, the timing of new bookings, risks associated with management of growth, reliance on third parties to supply key components of TriZetto's and CareKey's services, attraction and retention of employees, variability of quarterly operating results, competitive factors, other risks associated with acquisitions, changes in demand for third party products or solutions which form the basis of TriZetto's service and product offerings, financial stability of TriZetto's and CareKey's customers, the ability of TriZetto and CareKey to meet their contractual obligations to customers, including service level and disaster recovery commitments, changes in government laws and regulations and risks associated with rapidly changing technology, as well as the other risks identified in TriZetto's SEC filings, including, but not limited to, its annual report on Form 10-K and quarterly reports on Form 10-Q, copies of which may be obtained by contacting TriZetto's Investor Relations department at 949-719-2225 or at TriZetto's web site at www.trizetto.com. All information in this release is as of December 8, 2005. TriZetto undertakes no duty to update any forward-looking statement to conform the statement to actual results or changes in the company's expectations.

CONTACTS:

Investor Contact:
Brad Samson
949-719-2220
brad.samson@trizetto.com

Media Contact:
Audrey McDill
303-495-7197
audrey.mcdill@trizetto.com